Abstract

A series of substituted carboxylic acid hydrazides on reaction with substituted acetophenone gave
corresponding hydrazones which on Vilsmeier- Haack reaction resulted in corresponding formyl
pyrazoles. The structures of the newly synthesized compounds were confirmed on the basis of IR and 1HNMR. And also synthesized compounds were screened for their antibacterial (Staphylococcus aureus,
Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa) and antifungal (Aspergillus niger and
Candida albicans) activity. The results revealed that, compounds exhibited significant biological activity
against the tested microorganisms